Full folder duplication on some drives and partial on others possible?

I have a 6 drive pool. 4 local HDD's & 2 CloudDrives (1 Amazon & 1 MS).

I'd like to duplicate 2 folders in the pool. I'd like both Cloud Drive to keep a full set of the duplicated folders and I'd like 3 of the 4 local disks to keep a partial set of the duplicated folders.

Reasoning behind this is that I'd like full duplicated folder sets on the cloud storage for recovery if needed, but don't want to tie up the space with 3 full sets of duplicated folders on the local disk.

Possible?