Is there a way to firewall protect the drives

I have the drives in an external Probox setup, and I was wondering if there was any way to protect them from attacks such as ransomware? I have antivirus, anti malware, etc., and windows firewall, but what I was thinking is a way to firewall the programs that access to the drives. The data on the drivepool drives is only media that has a select group of programs that use it.